There are a few of us playing Borderlands these days (as you can see by the addition of a Borderlands channel on Vent) on PC. Here are some EXTREMELY helpful tweaks you can do to help make the gaming experience a little better. I HIGHLY recommend at least doing the tweaks to skip the 40 minutes of intro movies.
http://gbxforums.gearboxsoftware.com/showthread.php?t=79043
And as always, if you’re a member of Mayhem feel free to hop in to the Borderlands vent channel and join us.